Nerve damage caused by radiation therapy can begin quickly and get better, but most radiation-induced peripheral neuropathy takes months or years to cause problems and can worsen over time. A tumor might press on or grow into a nerve. Other cancer-related causes of neuropathy include: Other types of cancer treatment and cancer itself can damage nerves and cause neuropathy. Other cancer-related causes of neuropathy Please note that this link takes you to another ASCO website. This information is based on ASCO's recommendations for the Prevention and Management of Chemo-Induced Peripheral Neuropathy. Always talk with your doctor before taking any supplement or over-the-counter medication, because they can interact with cancer treatments. The American Society of Clinical Oncology (ASCO) does not recommend the use of the dietary supplement acetyl-L-carnitine or any medication or supplement to prevent peripheral neuropathy caused by chemotherapy. See below for more examples of conditions other than cancer that can cause neuropathy. This is an especially important step for people who already have neuropathy or who have conditions that may put them at greater risk of developing neuropathy, such as diabetes or a family history of nerve problems. They can tell you your risk for developing neuropathy after receiving chemotherapy. Vinca alkaloids, including vincristine (Vincasar), vinorelbine (Navelbine), and vinblastine (Velban)īefore cancer treatment begins, ask your doctor if any of the drugs in your treatment plan can cause damage to the nerves. Taxanes, including docetaxel (Docefrez and Taxotere) and paclitaxel (Taxol) Platinum-based chemotherapy, including cisplatin (Platinol), oxaliplatin (Eloxatin), and carboplatin (Paraplatin) When chemotherapy causes neuropathy, it is called "chemotherapy-induced peripheral neuropathy" or CIPN. Some types of chemotherapy drugs can cause neuropathy. If nerve problems worsen, your health care team may adjust your treatment. Talk to your health care team if you have any of these problems or notice changes in problems you have had for a while. Damage to autonomic nerves can cause:ĭigestive problems, such as diarrhea and constipation These nerves control the body functions you do not have to think about. Damage to motor nerves can cause:ĭifficulty using your hands and arms, making everyday activities like texting or buttoning a shirt a challengeĪutonomic nerves. These nerves send information between your brain and muscles. Problems knowing where your hands and feet are in space, causing difficulty walking or picking things up Pain that can feel like pinching, sharp stabs, burning, or electric shocksĭiscomfort that gets worse when you touch somethingĭifficulty feeling hot and cold or knowing if you hurt yourself These nerves affect your sense of feeling. Symptoms will depend on the type of nerve that is affected. There are 3 types of nerves that send messages to your brain and spinal cord: sensory nerves, motor nerves, and autonomic nerves. The symptoms you experience and how serious they are depend on which nerves are damaged and how many are damaged. Nerve problems are different for every person. Talk with your health care team about any symptoms you have, including new symptoms or changes in your symptoms. This is called palliative and supportive care. Treating and relieving side effects is an important part of cancer care and treatment. The specific problems depend on which nerves are affected.Ĭancer and cancer treatment can cause peripheral neuropathy. ![]() Neuropathy can cause problems related to sensing, feeling, and moving. Damage to your nerves in the peripheral nervous system is called peripheral neuropathy. Peripheral nerves send information between your brain and your body. All other nerves in the body are a part of the peripheral nervous system. The central nervous system is made up of the brain and spinal cord, a thick cord of nerves inside the spine. There are 2 parts to the nervous system: the central nervous system and the peripheral nervous system. ![]() The nervous system is the name of the network that the nerves form. ![]() Nerves are bundles of fibers in the body that help you sense, feel, and move.
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